Study 1: Factors associated with the initiation of testosterone replacement therapy in men from the 45 and Up Study
We used the original data from the 45 and Up Study baseline survey and linked PBS and MBS data to estimate the rate of initiation and continuation of testosterone replacement therapy among 45 and Up study male participants.
Men with self-rated poor health, those treated for osteoporosis, anxiety, depression or high blood cholesterol, and those who lived in major cities or were aged 55-74 years had greater odds of TRT initiation. The high rate of TRT initiation and low rate of recommended investigations suggest TRT may have been prescribed outside recommended indications.
Citation: Cheng Y, Bateson D, Concepcion K, Stewart M, Lowy M, Sweeney S, Estoesta J, McGeechan K. Factors associated with the initiation of testosterone replacement therapy in men from the’45 And Up Study’. Australian Journal of General Practice. 2018 Oct;47(10):698-706.
Study 2: Prevalence and associated factors of urinary leakage among women participating in the 45 and Up Study
We used the data from the 45 and Up Study baseline survey and follow-up survey to estimate the prevalence and identified the factors associated with urinary leakage.
Health professionals need to be aware of the high prevalence and of the associated factors such as high or low BMI, chronic conditions, psychological conditions and take into consideration the cultural and educational backgrounds of their patients. There may be a role for routine screening in primary care for urinary leakage in older women, particularly those with associated risk factors.
Citation: Concepcion K, Cheng Y, McGeechan K, Robertson S, Stewart M, Bateson D, Estoesta J, Chiarelli P. Prevalence and associated factors of urinary leakage among women participating in the 45 and Up Study. Neurourology and Urodynamics. 2018 Nov;37(8):2782-91.